KiKiKose Amandine Aviles


le 7 avril 2022

Ce kikikose aura lieu sur Teams uniquement.

Amandine Aviles, postdoctorante en toxicologie environnementale à la Syddansk Universitet en Danemark

Le jeudi 07 avril, le KiKikose sera animé par Amandine Aviles, postdoctorante en toxicologie environnementale à la Syddansk Universitet en Danemark.  Amandine est aussi candidate au poste de Maître de Conférences à l'IRBI. 

Résumé :
" Endocrine disrupting chemicals (EDCs) have become a major societal issue these past decades, due to their negative effects on human health. Indeed, EDCs are substances or mixtures of substances that affect the hormonal system and consequently induce deleterious effect on health. EDCs comprise, amongst other substances, chemicals present in everyday life products, like plasticizers. Bis-2(ethylhexyl) phthalate (DEHP), used in particular in PVC products, induces many detrimental effects in vertebrates, like changes in hormonal concentrations, alterations in the immune system, and behavioral disorders. However, while this pollutant is ubiquitously present in the environment, and the insects represent most of animal biodiversity, relatively few studies addressed the issue of DEHP effects on insects. In this context, my PhD project was to study the effects of DEHP on post-embryonic development and adult male sexual behavior in the European Coton Leafworm, Spodoptera littoralis. Results show that exposure to DEHP in food during larval stage alters concentrations of ecdysteroids (one of the main lipidic hormone family in insects), and ecdysteroid response gene expressions in larvae and adult males, and affects metabolism right before metamorphosis. Altered sexual behavior was also observed, but it depends of both DEHP and female pheromone concentrations.
I would like to keep studying the hormonal system in insects, focusing on the interactions between hormonal and immune systems in the Black Soldier Fly (BSF), Hermetia illucens. BSF is more and more used in industrial composters and as animal food. Despite this, fondamental studies on the biology of this species are still scarce. Indeed, while the BSF forage in an environmental full of bacteria, some of which are pathogeneous, underlying mecanisms for this resistance are still unknown. Besides, in insects, as in most pluricellular organisms, hormonal system is critical to integrate physiological and environmental signals, and maintain homeostasis. As a consequence, numerous environmental stresses (e.g. nutrition, temperature) can interfere with the hormonal system. Also, my research project at IRBI would be to study interactions between hormonal and immune systems in the BSF, in order to better understand effects of multiple stresses in insects. "